Oncogenes As Transcriptional Regulators, Volume 2: Cell Cycle Regulators and Chromosomal Translocation
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Bester Preis: Fr. 51.79 ( 52.79)¹ (vom 07.02.2018)
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9783034889346 - Birkhauser: Oncogenes as Transcriptional Regulators, Cell Cycle Regulators and Chromosomal Translocation
Birkhauser

Oncogenes as Transcriptional Regulators, Cell Cycle Regulators and Chromosomal Translocation (2013)

Lieferung erfolgt aus/von: Niederlande DE NW

ISBN: 9783034889346 bzw. 3034889348, in Deutsch, Birkhauser, neu.

Fr. 70.62 ( 71.98)¹ + Versand: Fr. 3.38 ( 3.45)¹ = Fr. 74.00 ( 75.43)¹
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Lieferung aus: Niederlande, Direct beschikbaar.
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The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes. The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character­ ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro­ teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral­ lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper­ toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel­ opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes. Inhoud:Taal: Engelstalig;EAN: 9783034889346;Bindwijze: E-book;Verschijningsdatum: 2013-11-27; Engelstalig | E-book | 9783034889346.
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9783034889346 - Jacques Ghysdael, Moshe Yaniv: Oncogenes as Transcriptional Regulators
Jacques Ghysdael, Moshe Yaniv

Oncogenes as Transcriptional Regulators (2013)

Lieferung erfolgt aus/von: Brasilien EN NW EB DL

ISBN: 9783034889346 bzw. 3034889348, in Englisch, Birkhäuser, Birkhäuser, Birkhäuser, neu, E-Book, elektronischer Download.

Fr. 51.79 (BRL 213.19)¹
versandkostenfrei, unverbindlich
Lieferung aus: Brasilien, in-stock.
The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character- ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro- teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral- lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper- toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel- opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.
3
9783034889346 - Herausgeber: Moshe Yaniv, Herausgeber: Jacques Ghysdael: Oncogenes As Transcriptional Regulators, Volume 2: Cell Cycle Regulators and Chromosomal Translocation
Herausgeber: Moshe Yaniv, Herausgeber: Jacques Ghysdael

Oncogenes As Transcriptional Regulators, Volume 2: Cell Cycle Regulators and Chromosomal Translocation (1997)

Lieferung erfolgt aus/von: Deutschland EN NW FE EB DL

ISBN: 9783034889346 bzw. 3034889348, in Englisch, 162 Seiten, Birkhäuser Basel, neu, Erstausgabe, E-Book, elektronischer Download.

Lieferung aus: Deutschland, E-Book zum Download.
The study of molecular events leading to cellular transformation and cancer has progressed considerably during the 1990s. It has become apparent that many genes subject to modification in cancer are, in fact, transcription factors that govern the execution of the genetic programme of the cell. Transcription factors can behave either as oncogenes or as tumor supressor genes. To date only a very limited number of transcription factors have been associated with cancer. This volume gives molecular information on several oncogenes, tumor suppressor genes or chromosomal translocations. Each chapter contains a description of the structure of such transcription factors, the nature of target genes, the regulation of their activities and an explaination of how they can deregulate cell growth and differentiation. This book should be suitable for the specialist scientist and the advanced student, Kindle Edition, Ausgabe: 1, Format: Kindle eBook, Label: Birkhäuser Basel, Birkhäuser Basel, Produktgruppe: eBooks, Publiziert: 1997-09-05, Freigegeben: 1997-09-05, Studio: Birkhäuser Basel.
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9783034889346 - Moshe Yaniv; Jacques Ghysdael: Oncogenes as Transcriptional Regulators
Moshe Yaniv; Jacques Ghysdael

Oncogenes as Transcriptional Regulators

Lieferung erfolgt aus/von: Vereinigtes Königreich Grossbritannien und Nordirland DE NW EB

ISBN: 9783034889346 bzw. 3034889348, in Deutsch, Springer Nature, neu, E-Book.

Fr. 62.91 (£ 56.99)¹
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Lieferung aus: Vereinigtes Königreich Grossbritannien und Nordirland, Lagernd.
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9783034889346 - Richard Talman: Oncogenes as Transcriptional Regulators : Cell Cycle Regulators and Chromosomal Translocation
Richard Talman

Oncogenes as Transcriptional Regulators : Cell Cycle Regulators and Chromosomal Translocation

Lieferung erfolgt aus/von: Vereinigtes Königreich Grossbritannien und Nordirland EN NW EB DL

ISBN: 9783034889346 bzw. 3034889348, in Englisch, Wiley, neu, E-Book, elektronischer Download.

Fr. 67.55 (£ 61.20)¹ + Versand: Fr. 11.03 (£ 9.99)¹ = Fr. 78.58 (£ 71.19)¹
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Lieferung aus: Vereinigtes Königreich Grossbritannien und Nordirland, Despatched same working day before 3pm.
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9783034889346 - Hamish Gordon: Oncogenes as Transcriptional Regulators : Cell Cycle Regulators and Chromosomal Translocation
Hamish Gordon

Oncogenes as Transcriptional Regulators : Cell Cycle Regulators and Chromosomal Translocation

Lieferung erfolgt aus/von: Vereinigtes Königreich Grossbritannien und Nordirland EN NW EB DL

ISBN: 9783034889346 bzw. 3034889348, in Englisch, Springer International Publishing, neu, E-Book, elektronischer Download.

Fr. 70.66 (£ 61.20)¹ + Versand: Fr. 8.07 (£ 6.99)¹ = Fr. 78.73 (£ 68.19)¹
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Lieferung aus: Vereinigtes Königreich Grossbritannien und Nordirland, Despatched same working day before 3pm.
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