Clinical Pharmacokinetics: A Short Introduction [Paperback] [Oct 01, 1990] Kr.
5 Angebote vergleichen

Lieferung aus: Vereinigte Staaten von Amerika, Versandkosten nach: USA.
Von Händler/Antiquariat, AffordableMedBooks.
Springer-Verlag, 1990-10-01. Paperback. Good. This is an ex-library book withdrawn from a medical school library in good condition and pages are clean. Minimal wear on outside due to being on shelf.

Lieferung aus: Vereinigte Staaten von Amerika, Usually ships in 2 to 4 weeks.
Von Händler/Antiquariat, Amazon.com.
The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under­ standing of changes in pharmacokinetics of drugs upon repeated administra­ tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose. Paperback, Ausgabe: 1, Label: Springer-Verlag, Springer-Verlag, Produktgruppe: Book, Publiziert: 1990-10, Studio: Springer-Verlag, Verkaufsrang: 15472045.

Lieferung aus: Vereinigte Staaten von Amerika, Versandkosten nach: USA.
Von Händler/Antiquariat, Ergodebooks.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen

Lieferung aus: Vereinigte Staaten von Amerika, zzgl. Versandkosten, Verandgebiet: DOM.
Von Händler/Antiquariat, Books Express, NH, Portsmouth, [RE:4].
Paperback.

Lieferung aus: Vereinigte Staaten von Amerika, zzgl. Versandkosten, Verandgebiet: DOM.
Von Händler/Antiquariat, ExtremelyReliable, TX, Richmond, [RE:4].
Paperback.