CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants
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CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants (2014)
ISBN: 9783659611230 bzw. 3659611239, in Deutsch, LAP Lambert Academic Publishing Sep 2014, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, AHA-BUCH GmbH [51283250], Einbeck, Germany.
This item is printed on demand - Print on Demand Titel. Neuware - Developing targeted genome regulation approaches holds much promise for accelerating trait discovery and development in agricultural biotechnology. The type II CRISPR/Cas system has been adapted for genome editing and transcriptional modulation purposes across a variety of organisms. Here, we employed this system for targeted transcriptional regulation in planta by developing chimeric dCas9-based activators and repressors. By fusing activator and repressor domains to the C-terminus of dCas9, respectively, we generated transcriptional activators: dCas9.EDLL and dCas9.TAD, as well as transcriptional repressor: dCas9.SRDX. Our data demonstrate that the dCas9.EDLL and dCas9.TAD activators, guided by gRNAs complementary to promoter elements, induce strong transcriptional activation on episomal targets in plant cells. Moreover, our data suggest that the dCas9.SRDX repressor and the dCas9.EDLL and dCas9.TAD activators are capable of markedly repressing or activating, respectively, the transcription of an endogenous genomic target. Our data indicate that the CRISPR/dCas9:TFs DNA targeting system can be used in plants as a functional genomic tool and for biotechnological applications. 88 pp. Englisch.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants (2014)
ISBN: 9783659611230 bzw. 3659611239, in Deutsch, LAP Lambert Academic Publishing, neu.
New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants
ISBN: 9783659611230 bzw. 3659611239, vermutlich in Englisch, neu, Hörbuch.
Developing targeted genome regulation approaches holds much promise for accelerating trait discovery and development in agricultural biotechnology. The type II CRISPR/Cas system has been adapted for genome editing and transcriptional modulation purposes across a variety of organisms. Here, we employed this system for targeted transcriptional regulation in planta by developing chimeric dCas9-based activators and repressors. By fusing activator and repressor domains to the C-terminus of dCas9, respectively, we generated transcriptional activators: dCas9.EDLL and dCas9.TAD, as well as transcriptional repressor: dCas9.SRDX. Our data demonstrate that the dCas9.EDLL and dCas9.TAD activators, guided by gRNAs complementary to promoter elements, induce strong transcriptional activation on episomal targets in plant cells. Moreover, our data suggest that the dCas9.SRDX repressor and the dCas9.EDLL and dCas9.TAD activators are capable of markedly repressing or activating, respectively, the transcription of an endogenous genomic target. Our data indicate that the CRISPR/dCas9:TFs DNA targeting system can be used in plants as a functional genomic tool and for biotechnological applications.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants
ISBN: 9783659611230 bzw. 3659611239, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants: Developing targeted genome regulation approaches holds much promise for accelerating trait discovery and development in agricultural biotechnology. The type II CRISPR/Cas system has been adapted for genome editing and transcriptional modulation purposes across a variety of organisms. Here, we employed this system for targeted transcriptional regulation in planta by developing chimeric dCas9-based activators and repressors. By fusing activator and repressor domains to the C-terminus of dCas9, respectively, we generated transcriptional activators: dCas9.EDLL and dCas9.TAD, as well as transcriptional repressor: dCas9.SRDX. Our data demonstrate that the dCas9.EDLL and dCas9.TAD activators, guided by gRNAs complementary to promoter elements, induce strong transcriptional activation on episomal targets in plant cells. Moreover, our data suggest that the dCas9.SRDX repressor and the dCas9.EDLL and dCas9.TAD activators are capable of markedly repressing or activating, respectively, the transcription of an endogenous genomic target. Our data indicate that the CRISPR/dCas9:TFs DNA targeting system can be used in plants as a functional genomic tool and for biotechnological applications. Englisch, Taschenbuch.
Crispr/Dcas9: TF Mediated Transcriptional Regulation in Plants (2014)
ISBN: 9783659611230 bzw. 3659611239, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, English-Book-Service Mannheim [1048135], Mannheim, Germany.
This item is printed on demand for shipment within 3 working days.
Crispr/Dcas9: TF Mediated Transcriptional Regulation in Plants
ISBN: 9783659611230 bzw. 3659611239, in Englisch, OmniScriptum GmbH & Co. KG, OmniScriptum GmbH & Co. KG, OmniScriptum GmbH & Co. KG, gebraucht.
Baazim Hatoon, Paperback, English-language edition, Pub by OmniScriptum GmbH & Co. KG.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants
ISBN: 3659611239 bzw. 9783659611230, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
CRISPR/dCas9:TF Mediated Transcriptional Regulation in Plants (2014)
ISBN: 9783659611230 bzw. 3659611239, vermutlich in Englisch, Taschenbuch, neu.
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