Development of Novel Peptide Inhibitors to BAG-1 - 8 Angebote vergleichen
| Preise | 2014 | 2018 | 2019 |
|---|---|---|---|
| Schnitt | Fr. 49.02 (€ 50.13)¹ | Fr. 48.80 (€ 49.90)¹ | Fr. 53.15 (€ 54.35)¹ |
| Nachfrage |
1
Development of Novel Peptide Inhibitors to BAG-1
~EN NW ABISBN: 9783659616921 bzw. 3659616923, vermutlich in Englisch, neu, Hörbuch.
Lieferung aus: Österreich, Lieferzeit: 5 Tage, zzgl. Versandkosten.
One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book is to identify and exploit a weakness at the molecular level of the anti-apoptotic pathway utilized by cancer cells to turn off the "triggered cell death" mechanism of apoptosis and survive chemotherapy. We specifically target the interaction between the anti-apoptotic protein Bcl-2 Associated Athanogene (BAG-1) and the 70-kilodalton Heat Shock Protein (HSP-70) that is suspected of driving the chemotherapeutic resistance, and seek to disrupt that interaction via peptidyl-biomimetically engineered peptides that are predicted via an in-house computational software named "Contact" and experimentally verified via Biacore (c) binding assays. The program "Contact" is now available for free download at http://www.engineering.vcu.edu/proteinengineering/.
One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book is to identify and exploit a weakness at the molecular level of the anti-apoptotic pathway utilized by cancer cells to turn off the "triggered cell death" mechanism of apoptosis and survive chemotherapy. We specifically target the interaction between the anti-apoptotic protein Bcl-2 Associated Athanogene (BAG-1) and the 70-kilodalton Heat Shock Protein (HSP-70) that is suspected of driving the chemotherapeutic resistance, and seek to disrupt that interaction via peptidyl-biomimetically engineered peptides that are predicted via an in-house computational software named "Contact" and experimentally verified via Biacore (c) binding assays. The program "Contact" is now available for free download at http://www.engineering.vcu.edu/proteinengineering/.
2
Development of Novel Peptide Inhibitors to BAG-1 - Applications of Peptidyl-Biomimetics to reduce and eliminate tumor resistance to chemotherapy
DE PB NWISBN: 9783659616921 bzw. 3659616923, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Lieferung aus: Deutschland, Versandkostenfrei.
Development of Novel Peptide Inhibitors to BAG-1: One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book is to identify and exploit a weakness at the molecular level of the anti-apoptotic pathway utilized by cancer cells to turn off the `triggered cell death` mechanism of apoptosis and survive chemotherapy. We specifically target the interaction between the anti-apoptotic protein Bcl-2 Associated Athanogene (BAG-1) and the 70-kilodalton Heat Shock Protein (HSP-70) that is suspected of driving the chemotherapeutic resistance, and seek to disrupt that interaction via peptidyl-biomimetically engineered peptides that are predicted via an in-house computational software named `Contact` and experimentally verified via Biacore (c) binding assays. The program `Contact` is now available for free download at engineering.vcu.edu/proteinengineering/, Englisch, Taschenbuch.
Development of Novel Peptide Inhibitors to BAG-1: One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book is to identify and exploit a weakness at the molecular level of the anti-apoptotic pathway utilized by cancer cells to turn off the `triggered cell death` mechanism of apoptosis and survive chemotherapy. We specifically target the interaction between the anti-apoptotic protein Bcl-2 Associated Athanogene (BAG-1) and the 70-kilodalton Heat Shock Protein (HSP-70) that is suspected of driving the chemotherapeutic resistance, and seek to disrupt that interaction via peptidyl-biomimetically engineered peptides that are predicted via an in-house computational software named `Contact` and experimentally verified via Biacore (c) binding assays. The program `Contact` is now available for free download at engineering.vcu.edu/proteinengineering/, Englisch, Taschenbuch.
3
Development of Novel Peptide Inhibitors to BAG-1
DE NWISBN: 3659616923 bzw. 9783659616921, in Deutsch, neu.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
4
Symbolbild
Development of Novel Peptide Inhibitors to BAG-1
EN NWISBN: 9783659616921 bzw. 3659616923, in Englisch, OmniScriptum GmbH & Co. KG, OmniScriptum GmbH & Co. KG, neu.
Lieferung aus: Vereinigte Staaten von Amerika, zzgl. Versandkosten, Free Shipping on eligible orders over $25.
Brunn Jonathan, Paperback, English-language edition, Pub by OmniScriptum GmbH & Co. KG.
Brunn Jonathan, Paperback, English-language edition, Pub by OmniScriptum GmbH & Co. KG.
5
Development of Novel Peptide Inhibitors to BAG-1 (2014)
~EN PB NWISBN: 9783659616921 bzw. 3659616923, vermutlich in Englisch, Taschenbuch, neu.
Lieferung aus: Deutschland, Next Day, Versandkostenfrei.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
6
Development of Novel Peptide Inhi (2014)
DE PB NWISBN: 9783659616921 bzw. 3659616923, in Deutsch, Taschenbuch, neu.
Lieferung aus: Deutschland, Next Day, Versandkostenfrei.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
7
Development of Novel Peptide Inhibitors to BAG-1 (2014)
DE PB NWISBN: 9783659616921 bzw. 3659616923, in Deutsch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Lieferung aus: Deutschland, Lieferbar in 2 - 3 Tage.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
8
Development of Novel Peptide Inhibitors to BAG-1 (2014)
~EN PB NWISBN: 9783659616921 bzw. 3659616923, vermutlich in Englisch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Lieferung aus: Schweiz, Versandfertig innert 4 - 7 Werktagen.
Applications of Peptidyl-Biomimetics to reduce and eliminate tumor resistance to chemotherapy, Taschenbuch, 08.11.2014.
Applications of Peptidyl-Biomimetics to reduce and eliminate tumor resistance to chemotherapy, Taschenbuch, 08.11.2014.
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